Day-1 genomics · the moat

The first AI that attests instead of guesses.

The genetics decide the treatment line. The clinician should not have to wait two weeks to see them.

14days for NGS to return

That is how long a sequencing panel takes to call NPM1, FLT3, and the rest. For two weeks the lesions that move a patient across a treatment line are a blank the clinician waits on.

The turn

Axiisium reads the molecular signal from the Day-1 bone-marrow morphology and signs a provisional prediction the same day, then resolves it against the confirmatory assay on a single cryptographic chain of custody. Not AI that guesses. AI that attests.

Acute myeloid leukemia cells in blood flow, isometric 3D illustration
Acute myeloid leukemia (AML) cells in blood flow, isometric view. 3D illustration © LASZLO, stock.adobe.com
One record, start to finish
Day 1 · morphology
NPM1 predicted
signedprovisionalresearch-use

The image model reads the smear and issues a probability, signed on the spot and marked pending wet-lab confirmation. The clinician can start planning; the record never calls it confirmed.

Days 2 to 14 · the assay runs
NGS in flight
Day ~14 · NGS assay
NPM1 confirmed
signedfinal

The wet-lab result resolves the Day-1 prediction on the same chain. Agree or disagree, the record shows exactly what was predicted and what was confirmed. Nothing is quietly rewritten.

0.894 ±0.066
Patient-level AUROC, NPM1 from morphology
Leakage-free 5-fold cross-validation
Preliminary; in the published literature range
(48 held-out patients, 8 NPM1-positive; external-cohort validation pending)

Models commoditize. A verifiable, signed chain from Day-1 prediction to confirmed genotype does not. That chain is the product.

Research use only. AI-predicted from morphology; provisional, pending wet-lab NGS confirmation. Not a diagnosis.

Research Use Only. Not for diagnostic use.